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Art. -Nr.: HY-179446

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HP1-IN-2

HP1-IN-2 (Compound (R)-18) is a HP1/H3K9me3 interaction inhibitor with an IC₅₀ of 18.1 μM. HP1-IN-2 can be used for studying various cancers with overexpression of HP1.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 1385556-53-5
Formel: C₁₉H₂₀N₂O₄
Molecular Weight:340.37

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

HP1-IN-2 Chemical Structure

CAS. Nr.: 1385556-53-5

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Preis

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

HP1-IN-2 (Compound (R)-18) is a HP1/H3K9me3 interaction inhibitor with an IC₅₀ of 18.1 μM. HP1-IN-2 can be used for studying various cancers with overexpression of HP1^[1].

Alle Histone Methyltransferase Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 1385556-53-5
Molecular Weight 340.37
Formel C₁₉H₂₀N₂O₄
SMILES

O=[N+]([O-])C1=CC=C(CN2[C@@H](C3=CC(OCCO4)=C4C=C3)CCC2)C=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Protokoll

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Tokuyama A, et al. Identification of a novel small-molecule inhibitor of heterochromatin protein 1. Bioorg Med Chem Lett. 2026 Feb 1;131:130469. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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