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Art. -Nr.: HY-186294

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Methyl-celastrol

Methyl-celastrol is a Celastrol (HY-13067) derivative and triterpenoid compound. Methyl-celastrol exists in Celastrus hypoleucus (Oliv) Warb f argutior Loes and other Celastraceae plants. Methyl-celastrol induces weight loss, reduces body fat, decreases food intake and improves glucose homeostasis. Methyl-celastrol is applicable to obesity-related research.

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CAS. Nr.: 1810867-99-2
Formel: C₃₀H₄₀O₄
Molecular Weight:464.64

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Methyl-celastrol Chemical Structure

CAS. Nr.: 1810867-99-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

In Vitro

Lipid Metabolism

Methyl-celastrol (Compound 18) induces weight loss, reduces body fat, decreases food intake, and improves glucose homeostasis in overweight and obese individuals^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Research Protocol for Metabolic Diseases

Chemical Information

CAS. Nr. 1810867-99-2
Molecular Weight 464.64
Formel C₃₀H₄₀O₄
SMILES

C[C@]12[C@@](C([C@@](CC1)3C)=CC=C(C(C)=C4OC)C3=CC4=O)(CC[C@@]5([C@@]2([H])C[C@@](C)(CC5)C(O)=O)C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Ralph Mazitschek, et al. Celastrol and derivatives for the treatment of obesity. WO2015148802A1. WIPO (PCT). 2015-03-26.

[2]. Yang H, et al. Targeting tumor proteasome with traditional Chinese medicine. Current drug discovery technologies. 2010 Mar;7(1):46-53. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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