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Art. -Nr.: HY-182425

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MI-23

MI-23 is a SARS-CoV-2 main protease (SARS-CoV-2 M_pro) inhibitor with an IC₅₀ of 7.6 nM. MI-23 is applicable to the research of COVID-19.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2698348-90-0
Formel: C₂₄H₂₉F₂N₃O₄
Molecular Weight:461.50

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

MI-23 Chemical Structure

CAS. Nr.: 2698348-90-0

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Preis

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Menge

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität

Beschreibung

MI-23 is a SARS-CoV-2 main protease (SARS-CoV-2 M_pro) inhibitor with an IC₅₀ of 7.6 nM. MI-23 is applicable to the research of COVID-19^[1].

Chemical Information

CAS. Nr. 2698348-90-0
Molecular Weight 461.50
Formel C₂₄H₂₉F₂N₃O₄
SMILES

O=C(NCC1)[C@@H]1C[C@@H](C=O)NC([C@@H]2[C@]3([H])[C@](CCC3)([H])CN2C(CCC4=CC(F)=CC(F)=C4)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Protokoll

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Qiao J, et al. SARS-CoV-2 M^pro inhibitors with antiviral activity in a transgenic mouse model. Science. 2021;371(6536):1374-1378. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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