NZ-804
NZ-804 is an orally active inhibitor for SARS-CoV-2 main protease Mpro with an IC50 of 8.9 nM. NZ-804 inhibits the SARS-CoV-2 replication in HeLa-hACE2 cell with an EC50 of 14 nM. NZ-804 exhibits board-spectrum antiviral activity aganst multiple CoVs. NZ-804 diminishes virus replication in mouse and hamster model.
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- CAS. Nr.: 2858658-44-1
- Formel: C27H23N3O3S
- Molecular Weight:469.55
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
IC50: 8.9 nM (SARS-CoV-2 Mpro)
Chemical Information
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CAS. Nr. 2858658-44-1
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Molecular Weight 469.55
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Formel C27H23N3O3S
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SMILES
O=C(N1CC/C(CC1)=C2C3=C(CS(=O)(C4=C/2C=CC=C4)=O)C=CC=C3)C5=CN=CC6=C5NC=C6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)