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Art. -Nr.: HY-125075

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PD 165929

PD 165929 is a high affinity and competitive non-peptide neuromedin-B (NMB) receptor selective antagonist (K_i: 6.3 nM; IC₅₀: 150 nM for rat NMB receptor).

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CAS. Nr.: 185215-75-2
Formel: C₃₇H₄₇N₅O₂
Molecular Weight:593.80

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

PD 165929 Chemical Structure

CAS. Nr.: 185215-75-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

PD 165929 is a high affinity and competitive non-peptide neuromedin-B (NMB) receptor selective antagonist (K_i: 6.3 nM; IC₅₀: 150 nM for rat NMB receptor)^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	0.35 μM Compound: 1	Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells Affinity of [125I][D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells	[PMID: 15149640]

Chemical Information

CAS. Nr. 185215-75-2
Molecular Weight 593.80
Formel C₃₇H₄₇N₅O₂
SMILES

CC(C)C(C=CC=C1C(C)C)=C1NC(N[C@](CC2=CNC3=CC=CC=C23)(C)C(NCC4(C5=CC=CC=N5)CCCCC4)=O)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. J.M. Eden, et al. PD 165929 -the first high affinity non-peptide neuromedin-B (NMB) receptor selective antagonist. Bioorganic & Medicinal Chemistry Letters. Volume 6, Issue 21

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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