BTN3A3
BTN3A3 shares the domain layout of BTN3A1 and BTN3A2 but, like BTN3A2, carries B30.2 substitutions that preclude high-affinity phosphoantigen binding. The protein is broadly expressed on immune cells and epithelia, with particularly notable detection in airway tissues. Beyond its cooperative role in γδ T cell responses, BTN3A3 has been identified as a ligand for the NK cell receptor NKp44, giving this paralog a role in innate cytotoxicity against tumor cells and virus-infected cells. Ongoing comparisons of the three BTN3 genes continue to clarify how their subtle differences shape phosphoantigen-driven and NK-mediated immunity.
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BTN3A3 Recombinant Proteins (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
