MAPKAPK3
MAPKAPK3, originally named 3pK and now often MK3, is the closest paralog of MK2. It is activated by p38 mitogen-activated protein kinase and, like MK2, phosphorylates small heat shock proteins including HSP27, sharing considerable substrate overlap and partly compensating for MK2 loss, which explains the milder inflammatory phenotype of MK2-null mice relative to p38 deletion. MK3 shows more restricted expression than MK2, and unique reported substrates such as the basic helix-loop-helix transcription factor E47 suggest additional roles in myogenic differentiation. The enzyme thus illustrates partial functional redundancy combined with isoform-specific specialization within the p38-activated kinase branch.
-
MAPKAPK3 Recombinant Proteins (2)
- Species:
- Source:
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
