SRMS/SRM
SRMS (Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation site, also called SRM) is an atypical Src-family member whose unwieldy name records its two structural anomalies: it lacks both the N-terminal myristoylation signal that anchors Src kinases at membranes and the C-terminal regulatory tyrosine phosphorylated by CSK. Free of these constraints, SRMS localizes to the cytoplasm and nucleus rather than the plasma membrane and may evade classical Src-family autoinhibition. SRMS is expressed during embryogenesis and in adult tissues. Reported substrates, including the RNA-binding protein Sam68, hint at roles in RNA processing, migration and proliferation, but SRMS remains one of the least characterized human tyrosine kinases, without drugs or firm disease associations.
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SRMS/SRM Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
