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Art. -Nr.: HY-N19911

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Pubetallin

Pubetallin is a germacrane-type sesquiterpenoid (germacranolide) can be found in the aerial parts of Sigesbeckia orientalis. Pubetallin induces cytotoxicity in breast cancer cells. Pubetallin can be used for the research of breast cancer.

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CAS. Nr.: 75207-37-3
Formel: C₂₀H₂₄O₇
Molecular Weight:376.40

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pubetallin Chemical Structure

CAS. Nr.: 75207-37-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
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Biologische Aktivität

Beschreibung

In Vitro

Anti-cancer

Pubetallin (24 h) shows moderate cytotoxicity against human MDA-MB-231 breast cancer cells with an IC₅₀ of 19.73 μM^[1].
Pubetallin (24 h) exhibits no significant cytotoxicity against human A549 lung cancer cells, with an IC₅₀ > 20 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS. Nr. 75207-37-3
Molecular Weight 376.40
Formel C₂₀H₂₄O₇
SMILES

C=C(C)C(O[C@@H]1[C@@H](OC)/C(C=O)=C\CC/C(CO)=C/[C@@]([C@]1([H])C2=C)([H])OC2=O)=O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Liu N, et al. Germacrane-type sesquiterpenoids with cytotoxic activity from Sigesbeckia orientalis. Bioorganic chemistry. 2019 Nov;92:103196. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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