Pyclen sulfate
Pyclen sulfate forms kinetically and thermodynamically stable nine-coordinate Ln (III) complexes, as well as Mn (II)-based MRI contrast agents. Pyclen-Based Mn(II) Complexes can be used for liver-specific MRI.
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- CAS. Nr.: 129135-03-1
- Formel: C11H20N4O4S
- Molecular Weight:304.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
In Vitro
Pyclen can form stable, highly luminescent lanthanide (III) complexes, which serve as one- and two-photon biological probes. These complexes stain living human breast cancer cells, exhibit no significant toxicity in the living Danio rerio (zebrafish) model, and enable high-quality in vivo two-photon microscopy imaging[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 129135-03-1
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Molecular Weight 304.37
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Formel C11H20N4O4S
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SMILES
O=S(=O)(O)O.N=1C2=CC=CC1CNCCNCCNC2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Hamon N, et al. Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications. J Am Chem Soc. 2020 Jun 3;142(22):10184-10197. [Content Brief]
[2]. Hall RC, et al. Manganese(II) EOB-Pyclen Diacetate for Liver-Specific MRI. ACS Appl Bio Mater. 2022;5(2):451-458. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)