RXR agonist 3
RXR agonist 3 (Compound 35) is a potent, partial RXR agonist (EC50s: 3, 3, 8 nM for RXRα, RXRβ, RXRγ, respectively). RXR agonist 3 can be used in the research of Alzheimer's disease, multiple sclerosis, and lymphoma.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C19H21F3N4O2
- Molecular Weight:394.39
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
RXR α 3 nM (EC50) |
RXRβ 3 nM (EC50) |
RXRγ 8 nM (EC50) |
Chemical Information
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Molecular Weight 394.39
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Formel C19H21F3N4O2
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SMILES
OC(CCNC1=NC(N2CCC(C)(C3=C2C=CC=C3)C)=CC(C(F)(F)F)=N1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)