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Art. -Nr.: HY-100915

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SKF 97541

(Synonyms: CGP 35024)

SKF 97541 (CGP 35024) is a potent and selective GABA_B agonist that can induce hyperpotential. SKF 97541 has antiepileptic activity.

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CAS. Nr.: 127729-35-5
Formel: C₄H₁₂NO₂P
Molecular Weight:137.12

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

SKF 97541 Chemical Structure

CAS. Nr.: 127729-35-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

SKF 97541 (CGP 35024) is a potent and selective GABA_B agonist that can induce hyperpotential. SKF 97541 has antiepileptic activity^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
CHO-K1	EC₅₀	41 nM Compound: 2	Agonist activity at human recombinant GABABreceptor expressed in CHO-K1 cells assessed as inhibition of intracellular calcium release by FLIPR Agonist activity at human recombinant GABABreceptor expressed in CHO-K1 cells assessed as inhibition of intracellular calcium release by FLIPR	[PMID: 18578471]

Chemical Information

CAS. Nr. 127729-35-5
Molecular Weight 137.12
Formel C₄H₁₂NO₂P
SMILES

O=P(C)(CCCN)O
Synonyms

CGP 35024
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Bon C, et al. Electrophysiological actions of GABAB agonists and antagonists in rat dorso-lateral septal neurones in vitro. Br J Pharmacol. 1996 Jun;118(4):961-7. [Content Brief]

[2]. Smirnova EY, et al. Presynaptic GABAB receptors underlie the antiepileptic effect of low-frequency electrical stimulation in the 4-aminopyridine model of epilepsy in brain slices of young rats. Brain Stimul. 2020 Sep-Oct;13(5):1387-1395. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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