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Sotrovimab

(Synonyms: VIR 7831; GSK-4182136)
5 Cited Publications
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Based on 5 publication(s) in Google Scholar

Sotrovimab (VIR 7831) is a human IgG1κ pan-sarbecovirus monoclonal antibody (mAb), neutralizes SARS-CoV-2, SARS-CoV-1, and multiple other sarbecoviruses. Sotrovimab is developed based on S309, exhibits a long half-life and great bioavailability in the respiratory mucosa. Sotrovimab could result in immune-mediated viral clearance and prevent progression of Covid-19 early in the course of disease.

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  • Reinheit: 96.80%
  • CAS. Nr.: 2423014-07-5
  • Molecular Weight:146.463 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Sotrovimab
  • Experimental Validation Results for Sotrovimab
  • Experimental Validation Results for Sotrovimab
  • Sotrovimab Chemical Structure
    Sotrovimab Chemical Structure
CAS. Nr.: 2423014-07-5
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized SARS-CoV-2/2019-nCoV Spike Protein (RBD, His Tag) can bind Sotrovimab. The EC50 for this effect is 1.47 ng/mL.

  • 1/16

    Loaded Sotrovimab on AHC2 biosensor, can bind SARS-CoV-2 S1 Protein (Omicron, B.1.1.529, His, HY-P74445) with an affinity constant of 1.168E-08 M as determined in BLI assay.

  • Sotrovimab Chemical Structure
    1/16
  • Sotrovimab
  • Immobilized SARS-CoV-2/2019-nCoV Spike Protein (RBD, His Tag) can bind Sotrovimab. The EC50 for this effect is 1.47 ng/mL.
  • Loaded Sotrovimab on AHC2 biosensor, can bind SARS-CoV-2 S1 Protein (Omicron, B.1.1.529, His, HY-P74445) with an affinity constant of 1.168E-08 M as determined in BLI assay.