SQ-33600
SQ-33600 is an HMG-CoA reductase inhibitor. SQ-33600 has cholesterol-lowering activity. SQ-33600 possesses cell-type selectivity, with much higher inhibitory activity on rat hepatocytes (IC50: 93 nM) than on human skin fibroblasts (IC50: 14200 nM). SQ-33600 can be used in the research of diseases such as hypercholesterolemia.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 133983-25-2
- Formel: C23H21FNNa2O5P
- Molecular Weight:487.37
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
Chemical Information
-
CAS. Nr. 133983-25-2
-
Molecular Weight 487.37
-
Formel C23H21FNNa2O5P
-
SMILES
O=C(C[C@@H](CP(C#CC(N1C2=CC=C(C=C2)F)=C(C3=C1C=CC=C3)C(C)C)(O[Na])=O)O)O[Na]
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Wang-Iverson D, et al. Determination of SQ 33,600, a phosphinic acid containing HMG CoA reductase inhibitor, in human serum by high-performance liquid chromatography combined with ionspray mass spectrometry. Biol Mass Spectrom. 1992 Apr;21(4):189-94. [Content Brief]
[2]. Jagoda E, et al. Radioimmunoassay for hydroxyphosphinyl-3-hydroxybutanoic acid (SQ 33,600), a hypocholesterolemia agent. Ther Drug Monit. 1993 Jun;15(3):213-9. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SQ-33600 Related Classifications
HY-19107 Related Classifications
Powered by Bioz