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Art. -Nr.: HY-14472S

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Tesofensine-d₅

(Synonyms: NS-2330-d₅)

Tesofensine-d₅ (NS-2330-d₅) is the deuterium labeled Tesofensine (HY-14472). Tesofensine (NS-2330) is a triple monoamine reuptake inhibitor inducing a potent inhibition of the re-uptake process in the synaptic cleft of the neurotransmitters dopamine (DA; IC₅₀=6.5 nM), norepinephrine (NE;IC₅₀=1.7 nM), and serotonin (5-HT;IC₅₀=11 nM), and with potentials as an anti-obesity agent. Tesofensine is a CNS acting anti-obesity agent.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₁₇H₁₈D₅Cl₂NO
Molecular Weight:333.31

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tesofensine-d₅ Chemical Structure

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Biologische Aktivität
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Biologische Aktivität

Beschreibung

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 195875-84-4
Molecular Weight 333.31
Formel C₁₇H₁₈D₅Cl₂NO
SMILES

CN1[C@@]2([H])[C@H](COC([2H])([2H])C([2H])([2H])[2H])[C@@H](C3=CC=C(Cl)C(Cl)=C3)C[C@]1([H])CC2
Synonyms

NS-2330-d₅
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.