ATB-343
ATB-343 is a derivative of Indomethacin that releases H2S. H2S has cytoprotective and anti-inflammatory effects, inhibiting leukocyte adhesion to vascular endothelium and leukocyte migration to inflammatory sites. ATB-343 can be used to suppress respiratory infections.
For research use only. We do not sell to patients.
- CAS No.: 1000700-26-4
- Formula: C28H20ClNO4S3
- Molecular Weight:566.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
3294.4 μM
Compound: 15
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Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
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[PMID: 28646655] |
| L02 | IC50 |
337.2 μM
Compound: 15
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Cytotoxicity against human LO2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
Cytotoxicity against human LO2 cells assessed as reduction in cell survival after 24 hrs by MTT assay
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[PMID: 28646655] |
Chemical Information
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CAS No. 1000700-26-4
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Molecular Weight 566.11
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Formula C28H20ClNO4S3
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SMILES
O=C(CC1=C(C)N(C(C2=CC=C(C=C2)Cl)=O)C3=C1C=C(C=C3)OC)OC4=CC=C(C(SS5)=CC5=S)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATB-343 Related Classifications
HY-15033 Related Classifications
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