Varsetatug
Based on 1 Customer Validation
Varsetatug (CX-2051 antibody) is a humanized IgG1κ monoclonal antibody inhibitor targeting EpCAM/TROP1/CD326. Varsetatug serves as the antibody component of the ADC compound CX-2051. It can be used in research on cancers including breast cancer, prostate cancer and ovarian cancer.
For research use only. We do not sell to patients.
- Purity: 97%
- CAS No.: 3036004-28-8
- Molecular Weight:155.116 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
EpCAM/TROP1/CD326
In Vitro
CX-2051 is a masked EpCAM antibody-drug conjugate (ADC) carrying a novel camptothecin-based topoisomerase I (Topo-I) payload, a linker, and an EpCAM-targeting antibody moiety (Varsetatug).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Loaded Varsetatug on ProA biosensor, can bind EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P72367) with an affinity constant of 1.693E-07 M as determined in BLI assay.
Chemical Information
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CAS No. 3036004-28-8
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Appearance Liquid
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Molecular Weight 155.116 kDa
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Color Colorless to light yellow
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SMILES
N/A
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Synonyms
CX-2051 antibody
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (257 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)