AP23848
AP23848 is an ATP-dependent kinase inhibitor that effectively and selectively targets the Kit activation loop mutation both in vitro and in vivo, showing anti-tumor activity. AP23848 can inhibit the phosphorylation of the activated Kit mutation and tumor growth in mice, making it suitable for targeting diseases with the D816V mutation, such as systemic mastocytosis (SM) and acute myeloid leukemia (AML) research.
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- CAS No.: 834894-21-2
- Formule: C30H38N5O2P
- Masse moléculaire:531.63
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 834894-21-2
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Masse moléculaire 531.63
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Formule C30H38N5O2P
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SMILES
OC1=CC=CC(CCN2C3=NC(C4CCCC4)=NC(NC5=CC=C(P(CCC)(CCC)=O)C=C5)=C3N=C2)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AP23848 Related Classifications
HY-107458 Related Classifications
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