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Cat. No.: HY-105721

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Aranotin

Aranotin strongly binds to Nsp15 viral protein. Aranotin can be used as promising SARS-CoV-2 replication strong inhibitor. Aranotin has the potential for COVID-19 research.

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CAS No.: 19885-51-9
Formule: C₂₀H₁₈N₂O₇S₂
Masse moléculaire:462.50

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Aranotin Chemical Structure

CAS No.: 19885-51-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Aranotin strongly binds to Nsp15 viral protein. Aranotin can be used as promising SARS-CoV-2 replication strong inhibitor. Aranotin has the potential for COVID-19 research^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
ASPC1	IC₅₀	11 μM Compound: 5	Cytotoxicity against human ASPC1 cells by SRB method Cytotoxicity against human ASPC1 cells by SRB method	[PMID: 37807846]
H69AR	IC₅₀	1.7 μM Compound: 5	Cytotoxicity against human NCI-H69AR cells by SRB method Cytotoxicity against human NCI-H69AR cells by SRB method	[PMID: 37807846]
K562	IC₅₀	1.4 μM Compound: 5	Cytotoxicity against human K562 cells by MTT method Cytotoxicity against human K562 cells by MTT method	[PMID: 37807846]
L02	IC₅₀	16 μM Compound: 5	Cytotoxicity against human L02 cells by SRB method Cytotoxicity against human L02 cells by SRB method	[PMID: 37807846]
MDA-MB-231	IC₅₀	0.7 μM Compound: 5	Cytotoxicity against human MDA-MB-231 cells by SRB method Cytotoxicity against human MDA-MB-231 cells by SRB method	[PMID: 37807846]

Chemical Information

CAS No. 19885-51-9
Masse moléculaire 462.50
Formule C₂₀H₁₈N₂O₇S₂
SMILES

O=C(N1[C@@]2([H])C3=COC=C[C@@H]2O)[C@@](C4)(SS[C@]1(C3)C5=O)N5[C@@]6([H])C4=COC=C[C@@H]6OC(C)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Suresh Kumar, et al. Identification of phytochemicals as potential therapeutic agents that binds to Nsp15 protein target of coronavirus (SARS-CoV-2) that are capable of inhibiting virus replication. Phytomedicine. 2021 May:85:153317. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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