Ataprost
Ataprost (ONO 41483) is an orally active Carboprostacyclin (HY-112322) analogue. Ataprost exhibits 2.6 times more active than Carboprostacyclin in inhibiting ADP-induced platelet aggregation in vitro. Ataprost has the ability to relieve coronary spasm.
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- CAS No.: 83997-19-7
- Formule: C21H32O4
- Masse moléculaire:348.48
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Platelet aggregation[1]
Ataprost inhibits platelet aggregation in human and baboon platelet rich plasma (PRP) with ED50s of 1.91 ng/mL and 4.38 ng/mL, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Ataprost (i.v.; single dose) inhibits platelet aggregation with an ED50 value of 3.2 μg/kg in baboon[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 83997-19-7
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Masse moléculaire 348.48
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Formule C21H32O4
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SMILES
O[C@@H](C1CCCC1)/C=C/[C@@H]2[C@](C/3)([H])[C@](CC3=C/CCCC(O)=O)([H])C[C@H]2O
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Synonyms
ONO 41483
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)