AtPep1
AtPep1 is an endogenous inducer of innate immune responses. AtPep1 can be isolated from Arabidopsis thaliana leaves. AtPep1 activates the transcription of defensin (PDF1.2), the expression of PROPEP1, the synthesis of hydrogen peroxide (H2O2) near leaf veins, and the alkalization of Arabidopsis suspension cell culture medium. AtPep1 induces the expression of genes encoding defensins and PR-1. AtPep1 is applicable to studies related to Pythium irregulare infection and pathogen infection.
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- CAS No.: 902781-11-7
- Formule: C104H183N39O32
- Masse moléculaire:2491.81
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
AtPep1 (20 min) induces medium alkalization in suspension-cultured Arabidopsis thaliana cells, with a half-maximal activity of approximately 0.25 nM[1].
AtPep1 (TFA) (10 nM; 2 h) induces the expression of PROPEP1 and PDF1.2 genes in detached leaves of *Arabidopsis thaliana* (Columbia ecotype). This response depends on functional jasmonic acid and ethylene pathways, and is partially dependent on NADPH oxidase activity[1].
AtPep1 (TFA) (10 nM; 2 h) induces vein-associated H2O2 accumulation in detached leaves of *Arabidopsis thaliana* (Columbia ecotype)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 902781-11-7
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Masse moléculaire 2491.81
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Formule C104H183N39O32
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Sequence
Ala-Thr-Lys-Val-Lys-Ala-Lys-Gln-Arg-Gly-Lys-Glu-Lys-Val-Ser-Ser-Gly-Arg-Pro-Gly-Gln-His-Asn
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Sequence Shortening
ATKVKAKQRGKEKVSSGRPGQHN
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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Fiche technique (259 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
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- Español - ES (252 KB)
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- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Huffaker A, et al. An endogenous peptide signal in Arabidopsis activates components of the innate immune response. Proc Natl Acad Sci U S A. 2006;103(26):10098-10103. [Content Brief]
[2]. Pearce G, et al. Structure-activity studies of AtPep1, a plant peptide signal involved in the innate immune response. Peptides. 2008;29(12):2083-2089. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AtPep1 Related Classifications
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