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Cat. No.: HY-130011

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CCG-232964

CCG-232964 is an orally active inhibitor of Rho/MRTF/SRF. CCG-232964 inhibits LPA-induced CTGF gene expression.

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CAS No.: 2349373-70-0
Formule: C₁₅H₁₅ClN₂O₃S
Masse moléculaire:338.81

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

CCG-232964 Chemical Structure

CAS No.: 2349373-70-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

CCG-232964 is an orally active inhibitor of Rho/MRTF/SRF. CCG-232964 inhibits LPA-induced CTGF gene expression^[1].

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Chemical Information

CAS No. 2349373-70-0
Masse moléculaire 338.81
Formule C₁₅H₁₅ClN₂O₃S
SMILES

O=C(O)CCCSC1=NN=C(C2=CC=C(C3CC3)C=C2Cl)O1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Kahl, Dylan, et al. 5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Reponse Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma. Journal of Medicinal Chemistry, (), acs.jmedchem.8b01772–.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Chemical Information
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Références

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CCG-232964

Voir tous les produits spécifiques à Isoform ROCK

Voir tous les produits spécifiques à Isoform Ras

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CCG-232964 Related Classifications

HY-130011 Related Classifications