Chlorin e6 trimethyl ester
Based on 1 publication(s) in Google Scholar
Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT).
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- Pureté : 99.81%
- CAS No.: 35038-32-5
- Formule: C37H42N4O6
- Masse moléculaire:638.75
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Chlorin e6 trimethyl ester
More
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>100 μM
Compound: chlorin-e6-trimethyl ester
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Dark toxicity in human HepG2 cells after overnight incubation by MTT assay
Dark toxicity in human HepG2 cells after overnight incubation by MTT assay
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[PMID: 26306981] |
| HepG2 | IC50 |
26.5 μM
Compound: chlorin-e6-trimethyl ester
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Photo cytotoxic activity against human HepG2 cells irradiated with 1.7 J/cm'2 light dose for 10 mins measured after overnight incubation by MTT assay
Photo cytotoxic activity against human HepG2 cells irradiated with 1.7 J/cm'2 light dose for 10 mins measured after overnight incubation by MTT assay
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[PMID: 26306981] |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 35038-32-5
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Appearance Solid
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Masse moléculaire 638.75
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Formule C37H42N4O6
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Color Brown to black
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SMILES
O=C(OC)C/C(C(NC(/C=C1C(CC)=C2C)=C3C)=C3C(OC)=O)=C(N=C(/C=C(C(C)=C/4C=C)\NC4=C/C2=N/1)[C@H]5C)\[C@H]5CCC(OC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Solvant et solubilité
In Vitro:
DMSO : 10 mg/mL (15.66 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (280 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5656 mL | 7.8278 mL | 15.6556 mL | 39.1389 mL |
| 5 mM | 0.3131 mL | 1.5656 mL | 3.1311 mL | 7.8278 mL | |
| 10 mM | 0.1566 mL | 0.7828 mL | 1.5656 mL | 3.9139 mL | |
| 15 mM | 0.1044 mL | 0.5219 mL | 1.0437 mL | 2.6093 mL |
Chlorin e6 trimethyl ester Related Classifications
HY-137475 Related Classifications
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