CoelPhos
CoelPhos is the cell-impermeable coelenterazine derivative. CoelPhos specifically recognizes extracellular GLuc and generates luminescent signals. CoelPhos is a practical bioluminescent tool for monitoring exocytic processes such as cell surface membrane fusion.
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- CAS No.: 1643661-02-2
- Formule: C33H33N6O7P
- Masse moléculaire:656.62
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
CoelPhos generates a detectable bioluminescent signal in HeLa cells expressing outer membrane-localized GLucM23, with an activity approximately 3-4% of that of native coelenterazine[1].
CoelPhos cannot cross the cell membrane, as it fails to generate a bioluminescent signal in HeLa cells expressing endoplasmic reticulum-localized GLucER[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1643661-02-2
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Masse moléculaire 656.62
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Formule C33H33N6O7P
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SMILES
O=C1C(CC2=CC=C(C=C2)OCCCN3N=NC(COCP(O)(O)=O)=C3)=NC4=C(CC5=CC=CC=C5)NC(C6=CC=C(O)C=C6)=CN14
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)