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Cat. No.: HY-158925

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Conglobatin C1

Name: Conglobatin C1
Brand: MedChemExpress
SKU: HY-158925
Price: 531.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Conglobatin C1 is a bacterial metabolite and has anticancer activity. Conglobatin C1 is cytotoxic to NS-1 mouse myeloma cells (IC₅₀ = 1.05 μg/mL) .

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CAS No.: 2673270-37-4
Formule: C₂₆H₃₄N₂O₆
Masse moléculaire:470.56

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Conglobatin C1 Chemical Structure

CAS No.: 2673270-37-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Conglobatin C1 is a bacterial metabolite and has anticancer activity. Conglobatin C1 is cytotoxic to NS-1 mouse myeloma cells (IC₅₀ = 1.05 μg/mL) .

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Chemical Information

CAS No. 2673270-37-4
Masse moléculaire 470.56
Formule C₂₆H₃₄N₂O₆
SMILES

O=C(/C(C)=C/CC[C@@H]([C@@H](OC(/C(C)=C/CC[C@@H]1C)=O)CC2=CN=CO2)C)O[C@H]1CC3=CN=CO3
Structure Classification
- Antibiotics
- Macrolide Antibiotics
Initial Source
- Microorganisms
Streptomyces
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Cell Biology

Cell Viability Determination by MTT Colorimetric Assay
The following protocol uses the MTT colorimetric assay as a classic literature-established method for assessing cell viability/metabolic activity in cultured mammalian cells. MTT[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] is reduced by metabolically active cells to a colored formazan product; the amount of formazan is quantified spectrophotometrically and provides an indirect measure of metabolically active viable cells. Importantly, MTT reduction reflects cellular oxidoreductase/metabolic activity rather than an absolute direct count of living cells, so changes in cellular metabolism can alter the signal independently of cell number.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Heather J Lacey, et al. Conglobatins B-E: cytotoxic analogues of the C2-symmetric macrodiolide conglobatin. J Antibiot (Tokyo). 2020 Nov;73(11):756-765. [Content Brief]

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Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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