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Cat. No.: HY-P3035

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Corazonin

Corazonin is a highly conserved neuropeptide hormone of wide-spread occurrence in insects, serves a central regulator of caste identity and behavior in social insects. Corazonin is also preferentially expressed in workers and/or foragers from other social insect species.

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CAS No.: 122929-08-2
Formule: C₆₂H₈₃N₁₇O₁₉
Masse moléculaire:1370.42

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Corazonin Chemical Structure

CAS No.: 122929-08-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vitro

Corazonin is produced by lateral brain neurosecretory cells projecting to the corpora cardiaca-corpora allata complex and in neurons of the ventral nerve cord^[1].
Corazonin evokes inward currents in Xenopus oocytes with an EC₅₀ value of 200 pM and leads to luminescence response from CHO cells with an EC₅₀ value of 75 pM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Corazonin (5.4 ng/brain; injection; single dose) suppresses expression of vitellogenin in the brain and stimulates worker-like hunting behaviors, while inhibiting gamergate behaviors, such as dueling and egg deposition in transitioning Harpegnathos individuals^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 122929-08-2
Masse moléculaire 1370.42
Formule C₆₂H₈₃N₁₇O₁₉
Sequence Shortening

{Pyr}-TFQYSRGWTN-NH2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (259 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Kim YJ, et al. Corazonin receptor signaling in ecdysis initiation. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6704-9. [Content Brief]

[2]. Gospocic J, et al. The Neuropeptide Corazonin Controls Social Behavior and Caste Identity in Ants. Cell. 2017 Aug 10;170(4):748-759.e12. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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