DMPEN
DMPEN (NSC 682691) (4-Demethylpenclomedine) is an alkylating metabolite of Penclomedine (HY-106401). DMPEN has an antitumor activity. DMPEN does not induce Purkinje cells loss with no significant neurocerebellar toxicity in rat cerebellum models. DMPEN can be used for cancers like breast and brain cancer research.
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- CAS No.: 176046-79-0
- Formule: C7H4Cl5NO2
- Masse moléculaire:311.38
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 176046-79-0
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Masse moléculaire 311.38
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Formule C7H4Cl5NO2
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SMILES
ClC1=C(OC)N=C(C(Cl)(Cl)Cl)C(Cl)=C1O
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Synonyms
NSC 682691; 4-Demethylpenclomedine
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. O'Reilly S, et al. The alkylating agent penclomedine induces degeneration of purkinje cells in the rat cerebellum. Invest New Drugs. 2003 Aug;21(3):269-79. [Content Brief]
[2]. Waud WR, et al. 4-Demethylpenclomedine, an antitumor-active, potentially nonneurotoxic metabolite of penclomedine. Cancer Res. 1997 Mar 1;57(5):815-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DMPEN Related Classifications
HY-13533 Related Classifications
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