Impdh2 - inosine monophosphate dehydrogenase 2 Gene
Also Known as IMPD; IMPD 2; IMPDH-II
Species: Mus musculus
Summary
Enables IMP dehydrogenase activity. Involved in 'de novo' XMP biosynthetic process and GMP biosynthetic process. Acts upstream of or within cellular response to interleukin-4; lymphocyte proliferation; and purine nucleotide biosynthetic process. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; heart; respiratory system; and sensory organ. Orthologous to human IMPDH2 (inosine monophosphate dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]
Impdh2 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001378921.1 | NP_001365850.1 | inosine-5'-monophosphate dehydrogenase 2 isoform 1 |
| NM_011830.5 | NP_035960.2 | inosine-5'-monophosphate dehydrogenase 2 isoform 2 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
inosine-5'-monophosphate dehydrogenase 2 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Nom du produit |
Effect
|
Pureté |
Rare Diseases
|
|---|---|---|---|---|
| HY-174221 | IMPDH II/HDAC1-IN-1 | Inhibitor | / | Unkown |
| HY-169296 | IMPDH2-IN-4 | Inhibitor | / | Unkown |
| HY-147342 | β-Benzamide adenine dinucleotide | Inhibitor | / | Unkown |
| HY-118917 | VX-148 | Inhibitor | / | Unkown |
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