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Cat. No.: HY-146651

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MPO-IN-4

MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC₅₀0 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT).

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CAS No.: 2088545-68-8
Formule: C₁₂H₁₁N₅
Masse moléculaire:225.25

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

MPO-IN-4 Chemical Structure

CAS No.: 2088545-68-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC₅₀0 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT)^[1].

Voir tous les produits spécifiques à Isoform Glutathione Peroxidase :

GPX1
GPX4

Chemical Information

CAS No. 2088545-68-8
Masse moléculaire 225.25
Formule C₁₂H₁₁N₅
SMILES

NC1=CC(CC2=CC=CC=C2)=C3N=NNC3=N1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Scott A Shaw, et al. Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorg Med Chem. 2020 Nov 15;28(22):115723. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

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Molecular Weight Molecular Weight

Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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MPO-IN-4

Voir tous les produits spécifiques à Isoform Glutathione Peroxidase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

MPO-IN-4 Related Classifications

HY-146651 Related Classifications