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Cat. No.: HY-N21614

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Phaeusmane F

Phaeusmane F is a eudesmane-type sesquiterpene that inhibits LPS (HY-D1056)-induced nitric oxide (NO) production in RAW 264.7 macrophages with an IC₅₀ of 4.8 μM. Phaeusmane F is found in the rhizomes of Curcuma phaeocaulis. Phaeusmane F can be used in research related to inflammatory responses.

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CAS No.: 1450839-78-7
Formule: C₁₅H₂₀O₅
Masse moléculaire:280.32

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (286 KB)

Phaeusmane F Chemical Structure

CAS No.: 1450839-78-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform NO Synthase :

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC50	4.8 μM	Inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages incubated for 24 h measured by Griess reagent assay with absorbance read at 540 nm. Inhibition of lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages incubated for 24 h measured by Griess reagent assay with absorbance read at 540 nm.	ejoc.201402465

In Vitro

Innate ImmunityOxidative Stress

Innate Immunity

Oxidative Stress

Phaeusmane F (compound 6) (24 h; 1 μg/mL LPS stimulation) inhibits LPS-induced NO production in RAW 264.7 macrophages with an IC₅₀ of 4.8 μM, without exhibiting significant cytotoxicity^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1450839-78-7
Masse moléculaire 280.32
Formule C₁₅H₂₀O₅
SMILES

C[C@]12[C@@]([C@](O)(CCC2=O)C)([H])CC([C@](C1)(O3)O)=C(C)C3=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (286 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Liu Y, et al. Eudesmane-Type Sesquiterpenes from Curcuma phaeocaulis and Their Inhibitory Activities on Nitric Oxide Production in RAW 264.7 Cells. Eur J Org Chem. 2014:5540-5548.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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