Phyllomedusin
Phyllomedusin, an tachykinin decapeptide, is a NK1 receptor agonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus.
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- CAS No.: 26145-48-2
- Formule: C52H82N16O13S
- Masse moléculaire:1171.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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NK1R |
Phyllomedusin (0.1 and 5 μg/kg, i.v.) has stimulant activity on the stomach of the anaesthetized rat[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Conscious rats[2].
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Dosage:30, 100, 300 μg/kg
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Administration:Intraperitoneal injection (i.p.)
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Result:Caused 75% delay in gastric emptying in conscious rats.
Chemical Information
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CAS No. 26145-48-2
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Masse moléculaire 1171.37
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Formule C52H82N16O13S
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Sequence Shortening
{Pyr}-NPNRFIGLM-NH2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Ganjiwale AD, et al. Three-dimensional structure of Phyllomedusin, a NK1 receptor agonist bound to dodecylphosphocholine micelles. J Struct Biol. 2009 Aug;167(2):176-84. [Content Brief]
[2]. Bertaccini G, et al. Effect of substance P and its natural analogues on gastric emptying of the conscious rat. Br J Pharmacol. 1981 Feb;72(2):221-3. [Content Brief]
[3]. Bertaccini G, et al. Action of some natural peptides on the stomach of the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1977 Jun;298(2):163-6. [Content Brief]
[4]. Sacco MA, et al. Kambo: Natural drug or potential toxic agent? A literature review of acute poisoning cases. Toxicol Rep. 2022 Apr 15;9:905-913. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Phyllomedusin Related Classifications
HY-P3092 Related Classifications
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