Retelliptine
Retelliptine (BD84), a derivative of ellipticine, is an inhibitor of Topoisomerase II with anticancer activity. Retelliptine can bind to DNA and inhibit Topoisomerase II during DNA replication.
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- CAS No.: 72238-02-9
- Formule: C25H32N4O
- Masse moléculaire:404.55
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Chemical Information
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CAS No. 72238-02-9
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Masse moléculaire 404.55
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Formule C25H32N4O
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SMILES
CCN(CC)CCCNC1=NC=CC2=C(C)C3=C(C4=CC(OC)=CC=C4N3)C(C)=C21
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Synonyms
BD84
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Kattan J, et al. Phase I study of retelliptine dihydrochloride (SR 95325 B) using a single two-hour intravenous infusion schedule[J]. American journal of clinical oncology, 1994, 17(3): 242-245. [Content Brief]
[2]. Maulard C, et al. Binding of retelliptine, a new antitumoral agent, to serum proteins and erythrocytes[J]. Biochemical pharmacology, 1990, 40(4): 895-898. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)