Spinorphin
Spinorphin is an inhibitor of enkephalin-degrading enzymes. Spinorphin inhibits aminopeptidase, dipeptidyl aminopeptidase III, angiotensin-converting enzyme and enkephalinase. Spinorphin possesses an antinociceptive effect.
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- CAS No.: 137201-62-8
- Formule: C45H64N8O10
- Masse moléculaire:877.04
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Oocyte | IC50 |
48.1 pM
Compound: 5, spinorphin
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Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of 20 nM LVVYPWA peptide by two electrode voltage clamping technique
Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of 20 nM LVVYPWA peptide by two electrode voltage clamping technique
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[PMID: 17676725] |
| Oocyte | IC50 |
8.3 pM
Compound: 5, spinorphin
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Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage clamping technique
Antagonist activity at human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current by two electrode voltage clamping technique
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[PMID: 17676725] |
Chemical Information
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CAS No. 137201-62-8
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Masse moléculaire 877.04
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Formule C45H64N8O10
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SMILES
C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CC1=CNC2=CC=CC=C12)NC([C@H]3N(C([C@H](CC4=CC=C(C=C4)O)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](CC(C)C)N)=O)=O)=O)=O)CCC3)=O)=O
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Synonyms
LVV-hemorphin-4
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Sequence
Leu-Val-Val-Tyr-Pro-Trp-Thr
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Sequence Shortening
LVVYPWT
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Spinorphin Related Classifications
HY-P1044 Related Classifications
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