TAP311
TAP311 is a cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 62 nM.
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- CAS No.: 1149362-88-8
- Formule: C34H40F6N6O4
- Masse moléculaire:710.71
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
IC50: 62 nM (CETP)[1]
Essai clinique
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1149362-88-8
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Masse moléculaire 710.71
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Formule C34H40F6N6O4
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SMILES
FC(F)(F)C1=CC(CN([C@@H]2C[C@H](CC)N(C(O[C@@H]3CC[C@@H](C(O)=O)CC3)=O)[C@H](CC)C2)C4=NC=C(C5=CN(C)N=C5)C=N4)=CC(C(F)(F)F)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)