VIR-165
VIR-165 is a modified form of virus inhibitory peptide (VIRIP) that binds the fusion peptide of the gp41 subunit and prevents its insertion into the target membrane. VIRIP inhibits a wide variety of human immunodeficiency virus type 1 (HIV-1) strains.
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- CAS No.: 943790-62-3
- Formule: C109H156N22O25S2
- Masse moléculaire:2238.67
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 943790-62-3
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Masse moléculaire 2238.67
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Formule C109H156N22O25S2
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Sequence
Leu-Glu-Ala-Ile-Pro-Cys-Ser-Ile-Pro-Pro-Cys-Phe-Ala-Phe-Asn-Lys-Pro-Phe-Val-Phe (Disulfide bridge: Cys6-Cys11)
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Sequence Shortening
LEAIPCSIPPCFAFNKPFVF (Disulfide bridge: Cys6-Cys11)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Münch J, et al. Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide. Cell. 2007 Apr 20;129(2):263-75. [Content Brief]
[2]. Eggink D, et al. HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein Spike. J Virol. 2016 Nov 14;90(23):10587-10599. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VIR-165 Related Classifications
HY-P1753 Related Classifications
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