VU0519975
Based on 1 Customer Validation
VU0519975 is a raft destabilizing compound. VU0519975 reduces PMP22 raft partitioning and destabilizes ordered domains. VU0519975 significantly decreases the fraction of phase separated GPMVs.
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- Pureté : 99.54%
- CAS No.: 1211788-57-6
- Formule: C17H17ClN4OS2
- Masse moléculaire:392.93
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 1211788-57-6
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Appearance Solid
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Masse moléculaire 392.93
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Formule C17H17ClN4OS2
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Color White to off-white
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SMILES
O=C(NC1=CC=CS1)N(CC2)CCN2C3=NC4=C(C(Cl)=CC=C4C)S3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (254.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureté et documentation
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Fiche technique (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5450 mL | 12.7249 mL | 25.4498 mL | 63.6246 mL |
| 5 mM | 0.5090 mL | 2.5450 mL | 5.0900 mL | 12.7249 mL | |
| 10 mM | 0.2545 mL | 1.2725 mL | 2.5450 mL | 6.3625 mL | |
| 15 mM | 0.1697 mL | 0.8483 mL | 1.6967 mL | 4.2416 mL | |
| 20 mM | 0.1272 mL | 0.6362 mL | 1.2725 mL | 3.1812 mL | |
| 25 mM | 0.1018 mL | 0.5090 mL | 1.0180 mL | 2.5450 mL | |
| 30 mM | 0.0848 mL | 0.4242 mL | 0.8483 mL | 2.1208 mL | |
| 40 mM | 0.0636 mL | 0.3181 mL | 0.6362 mL | 1.5906 mL | |
| 50 mM | 0.0509 mL | 0.2545 mL | 0.5090 mL | 1.2725 mL | |
| 60 mM | 0.0424 mL | 0.2121 mL | 0.4242 mL | 1.0604 mL | |
| 80 mM | 0.0318 mL | 0.1591 mL | 0.3181 mL | 0.7953 mL | |
| 100 mM | 0.0254 mL | 0.1272 mL | 0.2545 mL | 0.6362 mL |
VU0519975 Related Classifications
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