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Cat. No.: HY-126598

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Chaetoglobosin F

Chaetoglobosin F is a cytochalasan-based alkaloid from Chaetomium globosum. Chaetoglobosin F exhibits cytotoxicity against human nasopharyngeal epidermoid tumor cell KB, with IC₅₀ of 52.0 µM.

For research use only. We do not sell to patients.

CAS No.: 55945-75-0
Formula: C₃₂H₃₈N₂O₅
Molecular Weight:530.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Chaetoglobosin F Chemical Structure

CAS No.: 55945-75-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Endogenous Metabolite Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	3.2 μg/mL Compound: Cheatoglobosin F	Cytotoxicity against human HeLa cells Cytotoxicity against human HeLa cells	[PMID: 15497948]
KB	IC₅₀	52 μM Compound: 3	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 16499339]

Chemical Information

CAS No. 55945-75-0
Molecular Weight 530.65
Formula C₃₂H₃₈N₂O₅
SMILES

O=C([C@@H](O)CCC1=O)/C(C)=C/[C@@H](C)C/C=C/[C@]2([H])[C@]31C(N[C@@H](CC4=CNC5=C4C=CC=C5)[C@]3([H])[C@H](C)[C@]6(C)[C@@]2([H])O6)=O
Structure Classification
- Alkaloids
- Pyrrole Alkaloids
- Alkaloids
- Indole Alkaloids
Initial Source
- Microorganisms
Chaetomium globosum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ding G, et al., Chaetoglobosin U, a cytochalasan alkaloid from endophytic Chaetomium globosum IFB-E019. J Nat Prod. 2006 Feb;69(2):302-4. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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References

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Chaetoglobosin F

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Chaetoglobosin F Related Classifications

HY-126598 Related Classifications