CHI3L1-IN-5
Based on 1 Customer Validation
CHI3L1-IN-5 (Compound Z17) is a highly selective CHI3L1 inhibitor with a KD value of 6 μM. CHI3L1-IN-5 restores the clearance ability of astrocytes by rejuvenating lysosomal function and Aβ uptake. CHI3L1-IN-5 alleviates neuroinflammation by inhibiting the NF-κB pathway. CHI3L1-IN-5 can be used for research on Alzheimer's disease.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 98.60%
- CAS No.: 2249043-42-1
- Formule: C19H22FN3O2
- Masse moléculaire:343.40
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Chemical Information
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CAS No. 2249043-42-1
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Appearance Solid
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Masse moléculaire 343.40
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Formule C19H22FN3O2
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Color White to light yellow
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SMILES
O=C(C1=CC(C=CC=C2F)=C2N=C1)N3CCCCC3CC(NCC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (291.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9121 mL | 14.5603 mL | 29.1206 mL | 72.8014 mL |
| 5 mM | 0.5824 mL | 2.9121 mL | 5.8241 mL | 14.5603 mL | |
| 10 mM | 0.2912 mL | 1.4560 mL | 2.9121 mL | 7.2801 mL | |
| 15 mM | 0.1941 mL | 0.9707 mL | 1.9414 mL | 4.8534 mL | |
| 20 mM | 0.1456 mL | 0.7280 mL | 1.4560 mL | 3.6401 mL | |
| 25 mM | 0.1165 mL | 0.5824 mL | 1.1648 mL | 2.9121 mL | |
| 30 mM | 0.0971 mL | 0.4853 mL | 0.9707 mL | 2.4267 mL | |
| 40 mM | 0.0728 mL | 0.3640 mL | 0.7280 mL | 1.8200 mL | |
| 50 mM | 0.0582 mL | 0.2912 mL | 0.5824 mL | 1.4560 mL | |
| 60 mM | 0.0485 mL | 0.2427 mL | 0.4853 mL | 1.2134 mL | |
| 80 mM | 0.0364 mL | 0.1820 mL | 0.3640 mL | 0.9100 mL | |
| 100 mM | 0.0291 mL | 0.1456 mL | 0.2912 mL | 0.7280 mL |
CHI3L1-IN-5 Related Classifications
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