1. Cell Cycle/DNA Damage
  2. Checkpoint Kinase (Chk)
  3. CHK1-IN-4

CHK1-IN-4 

Cat. No.: HY-128766
Handling Instructions

CHK1-IN-4 (Compound 3) is a potent checkpoint kinase 1 (chk1) inhibitor, and potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 has anti-tumor activity.

For research use only. We do not sell to patients.

CHK1-IN-4 Chemical Structure

CHK1-IN-4 Chemical Structure

CAS No. : 2120398-41-4

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All Checkpoint Kinase (Chk) Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

CHK1-IN-4 (Compound 3) is a potent checkpoint kinase 1 (chk1) inhibitor, and potently inhibits chk1 phosphorylation in the tumor cells. CHK1-IN-4 has anti-tumor activity[1].

IC50 & Target[1]

Chk1

 

In Vivo

CHK1-IN-4 (Compound 3) (40 mg/kg, IV, twice a week) alone enhances anti-tumor growth activity of CPT1 in the tumor model[1].

Molecular Weight

444.29

Formula

C₁₈H₁₈BrN₇O₂

CAS No.

2120398-41-4

SMILES

N#CC1=NC=C(NC2=NNC(C3=C(OC)C=C(Br)C=C3OCCCN)=C2)N=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

CHK1-IN-4Checkpoint Kinase (Chk)Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
CHK1-IN-4
Cat. No.:
HY-128766
Quantity:
MCE Japan Authorized Agent: