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Cat. No.: HY-184824

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CK2-IN-18

CK2-IN-18 is a protein kinase CK2 inhibitor with an IC₅₀ of > 30 μM against protein kinase CK2. CK2-IN-18 can be used in studies related to CK2-mediated signaling pathways, such as various cancers including lung cancer and breast cancer.

For research use only. We do not sell to patients.

CAS No.: 1417638-06-2
Formula: C₁₄H₁₅N₃O₄
Molecular Weight:289.29

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CK2-IN-18 Chemical Structure

CAS No.: 1417638-06-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target^[1]

CK2

All Casein Kinase Isoforms :

In Vitro

CK2-IN-18 (compound 19) does not potently inhibit recombinant human CK2, with an IC₅₀ greater than 30 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1417638-06-2
Molecular Weight 289.29
Formula C₁₄H₁₅N₃O₄
SMILES

O=C1N=C(NC(CCC)=C1)NC2=CC=C(C(C(O)=O)=C2)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Chekanov MO, et al. Design, synthesis and biological evaluation of 2-aminopyrimidinones and their 6-aza-analogs as a new class of CK2 inhibitors. Journal of enzyme inhibition and medicinal chemistry. 2014 Oct;29(5):639-46. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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CK2-IN-18

All Casein Kinase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

CK2-IN-18 Related Classifications

HY-184824 Related Classifications