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Cat. No.: HY-118244

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Clathrin-IN-3

Clathrin-IN-3 (Compound 25) is a Clathrin inhibitor (IC₅₀: 6.9 μM). Clathrin-IN-3 potenly inhibits clathrin terminal domain-amphiphysin PPI.

For research use only. We do not sell to patients.

CAS No.: 1419321-16-6
Formula: C₁₉H₁₂KNO₅S
Molecular Weight:405.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Clathrin-IN-3 Chemical Structure

CAS No.: 1419321-16-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Clathrin-IN-3 (Compound 25) is a Clathrin inhibitor (IC₅₀: 6.9 μM). Clathrin-IN-3 potenly inhibits clathrin terminal domain-amphiphysin PPI^[1].

Chemical Information

CAS No. 1419321-16-6
Molecular Weight 405.47
Formula C₁₉H₁₂KNO₅S
SMILES

O=C(N(C1=O)CC2=CC=CC=C2)C3=C4C1=CC=CC4=CC(S(=O)(O[K])=O)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. MacGregor KA, et al. Development of 1,8-naphthalimides as clathrin inhibitors. J Med Chem. 2014 Jan 9;57(1):131-43. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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