Clomazone-d4
Clomazone-d4 is the deuterated-labeled Clomazone (HY-W040194). Clomazone is a broad spectrum herbicide, mainly used to control annual broadleaf weeds and grass weeds in various crops such as rice, soybeans, and peanuts. Clomazone inhibits carotenoid biosynthesis, and treated plants show typical "albinism" symptoms due to the destruction of chloroplast membrane structure leading to chlorophyll degradation. Clomazone exhibits multiple toxic effects on non-target organisms, including aquatic lethality, developmental malformations, liver damage, mitochondrial dysfunction, and hematotoxicity.
For research use only. We do not sell to patients.
- Formula: C12H10D4ClNO2
- Molecular Weight:243.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 81777-89-1
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Molecular Weight 243.72
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Formula C12H10D4ClNO2
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SMILES
O=C1N(CC2=C([2H])C([2H])=C([2H])C([2H])=C2Cl)OCC1(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Stevanovic M, et al. Toxicity of clomazone and its formulations to zebrafish embryos (Danio rerio). Aquat Toxicol. 2017 Jul;188:54-63. [Content Brief]
[2]. Dos Santos Silva HP, et al. Ametryn and Clomazone Disrupt Mitochondrial Bioenergetics in Rat Liver: Evidence for Inhibition of Complexes I and II and ATP Synthase. Toxics. 2025 Sep 16;13(9):784. [Content Brief]
[3]. Tang HB, et al. Herbicide clomazone induced hematotoxicity and hepatic compensatory responses in the invasive turtle, Trachemys scripta elegans. Aquat Toxicol. 2025 Sep;286:107470. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Clomazone-d4 Related Classifications
HY-W725475 Related Classifications
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