Copper sulfate pentahydrate, for cell culture, 98%

Name: Copper sulfate pentahydrate, for cell culture, 98%
Brand: MedChemExpress
SKU: HY-Y1881B
Rating: 4.5 (1 reviews)

製品番号: HY-Y1881B 純度: 99.99%: Data Sheet SDS COA 取扱説明書
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Copper sulfate pentahydrate, for cell culture, 98% is a biochemical reagent. Copper sulfate pentahydrate, for cell culture, 98% reduces the production of ROS and the expression levels of MyD88 as well as c-Rel genes. Copper sulfate pentahydrate, for cell culture, 98% decreases the activities of T-SOD, CAT, and GSH, increases the activities of caspase-3, caspase-8, and caspase-9. Copper sulfate pentahydrate, for cell culture, 98% is cytotoxic to various cells.

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Copper sulfate pentahydrate, for cell culture, 98% 構造式

CAS 番号 : 7758-99-8

容量	価格（税別）	在庫状況	数量
25 g	$25	在庫あり	Estimated Time of Arrival: December 31
50 g		お問い合わせ

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* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of Copper sulfate pentahydrate, for cell culture, 98%:

Copper sulfate pentahydrate, 99.9% 在庫あり

顧客検証

•Cell Death Dis. 2026 Mar 26;17(1):381.

Caspase アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Caspase 1 Caspase 2 Caspase 3 Caspase 4 Caspase 5 Caspase 6 Caspase 7 Caspase 8 Caspase 9 Caspase 10 Caspase 12 Caspase Caspase 11 Caspase-13

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

IC₅₀ & Target^[1]^[2]^[3]

Caspase-3

Caspase-8

Caspase-9

体外実験

Copper sulfate pentahydrate (6.25-200 mg/mL; 24 h), for cell culture, 98% significantly decreases the cell viability of three human intestinal epithelial cell lines (HCT116, HT-29 and SW480)^[1].
Copper sulfate (2.4 mg Cu/L; 24 h) significantly decreases the viability of primary hepatocytes of Epinephelus coioides^[2].
Copper sulfate (5-100 µM) has no effect on CHO cell growth or antibody production, with a slight dose-dependent decrease in culture viability^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis^[2]

Cell Line:	primary hepatocytes of Epinephelus coioides
Concentration:	2.4 mg Cu/L
Incubation Time:	24 h
Result:	Increased the percentages of apoptosis and necrosis. Increased the activities of caspase-3, caspase-8, and caspase-9.

分子量

249.69

分子式

CuSO₄·5H₂O

CAS 番号

7758-99-8

Appearance

Solid

Color

Light blue to blue

SMILES

[CuSO4 ?5H2O]

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Store at room temperature, keep dry and cool

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature, keep dry and cool)

溶剤 & 溶解度

体外:

H₂O : 50 mg/mL (200.25 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.0050 mL	20.0248 mL	40.0497 mL
5 mM	0.8010 mL	4.0050 mL	8.0099 mL
10 mM	0.4005 mL	2.0025 mL	4.0050 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.99%

Select Batch:

データシート (273 KB) SDS (698 KB)

COA (243 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Feyzi A, et al. Copper sulfate pentahydrate reduced epithelial cytotoxicity induced by lipopolysaccharide from enterogenic bacteria. Biomed Pharmacother. 2017 May;89:454-461. [Content Brief]

[2]. Wang T, et al. Copper Nanoparticles and Copper Sulphate Induced Cytotoxicity in Hepatocyte Primary Cultures of Epinephelus coioides. PLoS One. 2016 Feb 18;11(2):e0149484. [Content Brief]

[3]. Chaderjian WB, et al. Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed. Biotechnol Prog. 2005 Mar-Apr;21(2):550-3. [Content Brief]

[4]. NAKASHIMA, K. et al.Membrane protein cross-linking is an early step in the pathogenesis of copper-induced hemolytic </b><b>anemia </b> Biomedical Research, 1(6), 548–551.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.0050 mL	20.0248 mL	40.0497 mL	100.1242 mL
	5 mM	0.8010 mL	4.0050 mL	8.0099 mL	20.0248 mL
	10 mM	0.4005 mL	2.0025 mL	4.0050 mL	10.0124 mL
	15 mM	0.2670 mL	1.3350 mL	2.6700 mL	6.6749 mL
	20 mM	0.2002 mL	1.0012 mL	2.0025 mL	5.0062 mL
	25 mM	0.1602 mL	0.8010 mL	1.6020 mL	4.0050 mL
	30 mM	0.1335 mL	0.6675 mL	1.3350 mL	3.3375 mL
	40 mM	0.1001 mL	0.5006 mL	1.0012 mL	2.5031 mL
	50 mM	0.0801 mL	0.4005 mL	0.8010 mL	2.0025 mL
	60 mM	0.0667 mL	0.3337 mL	0.6675 mL	1.6687 mL
	80 mM	0.0501 mL	0.2503 mL	0.5006 mL	1.2516 mL
	100 mM	0.0400 mL	0.2002 mL	0.4005 mL	1.0012 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.