Coumarin 7
Based on 1 Customer Validation
Coumarin 7 is a coumarin laser dye in plants in the form of glycosides.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 27425-55-4
- Formula: C20H19N3O2
- Molecular Weight:333.38
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| B16 | IC50 |
12.6 μM
Compound: 7
|
Antiproliferative activity against mouse B16 cell line
Antiproliferative activity against mouse B16 cell line
|
[PMID: 16793260] |
| DLD-1 | IC50 |
>70 μM
Compound: 7
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Antiproliferative activity against human DLD1 cell line
Antiproliferative activity against human DLD1 cell line
|
[PMID: 16793260] |
| H9 | CC50 |
>50 μM
Compound: 53
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Cytotoxicity against human H9 cells by MTS assay
Cytotoxicity against human H9 cells by MTS assay
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[PMID: 25847768] |
| H9 | IC50 |
0.24 μM
Compound: 53
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Antiviral activity against X4 tropic HIV-1 clone pNL4-3 infected in H9 cells assessed as reduction in p24 antigen after 4 days by ELISA
Antiviral activity against X4 tropic HIV-1 clone pNL4-3 infected in H9 cells assessed as reduction in p24 antigen after 4 days by ELISA
|
[PMID: 25847768] |
| HeLa | IC50 |
>70 μM
Compound: 7
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Antiproliferative activity against human HeLa cell line
Antiproliferative activity against human HeLa cell line
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[PMID: 16793260] |
| HUVEC | IC50 |
9.6 μM
Compound: 7
|
Antiproliferative activity against HUVEC cell line
Antiproliferative activity against HUVEC cell line
|
[PMID: 16793260] |
| NIH3T3 | IC50 |
9.3 μM
Compound: 7
|
Antiproliferative activity against mouse NIH3T3 cell line
Antiproliferative activity against mouse NIH3T3 cell line
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[PMID: 16793260] |
| SiHa | IC50 |
62.1 μM
Compound: 7
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Antiproliferative activity against human SiHa cell line
Antiproliferative activity against human SiHa cell line
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[PMID: 16793260] |
| U-87MG ATCC | IC50 |
15 μM
Compound: 7
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Antiproliferative activity against human U87 MG cell line
Antiproliferative activity against human U87 MG cell line
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[PMID: 16793260] |
Coumarin 7 has the maximum CL intensity (Imax=0.39×10-9 photon/sml), total amount of light (S=0.07×10-10 photon/mL) and the yield of CL (φCL=0.12×108 Einstein/mol)[2]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS No. 27425-55-4
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Appearance Solid
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Molecular Weight 333.38
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Formula C20H19N3O2
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Color Light yellow to yellow
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SMILES
O=C1C(C2=NC3=CC=CC=C3N2)=CC4=CC=C(N(CC)CC)C=C4O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 12.5 mg/mL (37.49 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9996 mL | 14.9979 mL | 29.9958 mL | 74.9895 mL |
| 5 mM | 0.5999 mL | 2.9996 mL | 5.9992 mL | 14.9979 mL | |
| 10 mM | 0.3000 mL | 1.4998 mL | 2.9996 mL | 7.4990 mL | |
| 15 mM | 0.2000 mL | 0.9999 mL | 1.9997 mL | 4.9993 mL | |
| 20 mM | 0.1500 mL | 0.7499 mL | 1.4998 mL | 3.7495 mL | |
| 25 mM | 0.1200 mL | 0.5999 mL | 1.1998 mL | 2.9996 mL | |
| 30 mM | 0.1000 mL | 0.4999 mL | 0.9999 mL | 2.4997 mL |
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