1. Metabolic Enzyme/Protease
  2. NADPH Oxidase
  3. CPP11G

CPP11G (Compound 11g) is a highly selective NADPH oxidase 2 (Nox2) inhibitor (IC50=20 μM). CPP11G is promising for research of inflammatory diseases (e.g., vasculitis, atherosclerosis) and Nox2-overactivated pathologies (e.g., ischemia-reperfusion injury).

For research use only. We do not sell to patients.

CPP11G

CPP11G Chemical Structure

CAS No. : 1580464-93-2

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Description

CPP11G (Compound 11g) is a highly selective NADPH oxidase 2 (Nox2) inhibitor (IC50=20 μM). CPP11G is promising for research of inflammatory diseases (e.g., vasculitis, atherosclerosis) and Nox2-overactivated pathologies (e.g., ischemia-reperfusion injury)[1][2].

IC50 & Target

NOX2

20 μM (IC50)

Molecular Weight

390.40

Formula

C22H32BrN

CAS No.
SMILES

CC(C[C@H]1[C@@]2([H])C3=C(Br)C=CC=C3[C@@](CC2(C)C)([H])N1CCCCC)=C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CPP11G
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HY-185008
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