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Cat. No.: HY-168736

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CRC-IN-1

CRC-IN-1 (compound (-)-15h) is a potent anti-colorectal cancer (CRC) agent, as well as a derivative of the anticancer agent Evodiamine (HY-N0114).

For research use only. We do not sell to patients.

CAS No.: 3023350-74-2
Formula: C₃₄H₃₃F₂N₅O₆
Molecular Weight:645.65

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

CRC-IN-1 Chemical Structure

CAS No.: 3023350-74-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

CRC-IN-1 (compound (-)-15h) is a potent anti-colorectal cancer (CRC) agent, as well as a derivative of the anticancer agent Evodiamine (HY-N0114)^[1].

Chemical Information

CAS No. 3023350-74-2
Molecular Weight 645.65
Formula C₃₄H₃₃F₂N₅O₆
SMILES

O=C(N(CCC1=C2NC3=C1C=C(OC([C@@H](NC(OC(C)(C)C)=O)CCC(N)=O)=O)C=C3)[C@]2([H])N4C5=CC=CC(F)=C5)C6=C4C=CC(F)=C6
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chen S, et al. Structure-activity relationship study of novel evodiamine amino acid conjugates with potent anti-colorectal cancer efficacy. Eur J Med Chem. 2024 Dec 3;283:117132. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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