Cy5.5-COOH
Based on 1 Customer Validation
Cy5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye that emits fluorescence at 710 nm upon excitation at 650 nm. Cy5.5-COOH possesses excellent spectral properties, including a narrow absorption spectrum, high sensitivity, and stability. Cy5.5-COOH can be used for bioimaging and disease diagnosis.
For research use only. We do not sell to patients.
- Purity: 98.82%
- CAS No.: 1449612-07-0
- Formula: C40H42N2O2
- Molecular Weight:582.77
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
Brief steps for labeling polypropylene (PP) microplastics with Cy5.5-COOH for bioimaging[1]:
1. Labeling PP microplastics: Mix PP microplastics with tetrahydrofuran and distilled water, add Cy5.5-COOH solution in DMSO, stir for 4 days, then filter, wash, and dry.
2. Verifying labeling efficiency: Confirm particle size and morphology via SEM and PSA, validate chemical structure by FT-IR, and detect fluorescence intensity using IVIS imaging.
3. Stability tests: Evaluate fluorescence stability in corn oil and digestive stability in simulated gastrointestinal fluids.
4. Biodistribution study: After oral administration of Cy-PP to mice, monitor real-time in vivo distribution at different time points via IVIS, and detect fluorescence signals in organs and feces at 24 hours.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1449612-07-0
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Appearance Solid
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Molecular Weight 582.77
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Formula C40H42N2O2
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Color Brown to reddish brown
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SMILES
C[N+]1=C(/C=C/C=C/C=C2N(CCCCCC([O-])=O)C3=C(C4=CC=CC=C4C=C3)C/2(C)C)C(C)(C)C5=C1C=CC6=CC=CC=C56
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Synonyms
Cyanine 5.5 carboxylic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 50 mg/mL (85.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7159 mL | 8.5797 mL | 17.1594 mL | 42.8986 mL |
| 5 mM | 0.3432 mL | 1.7159 mL | 3.4319 mL | 8.5797 mL | |
| 10 mM | 0.1716 mL | 0.8580 mL | 1.7159 mL | 4.2899 mL | |
| 15 mM | 0.1144 mL | 0.5720 mL | 1.1440 mL | 2.8599 mL | |
| 20 mM | 0.0858 mL | 0.4290 mL | 0.8580 mL | 2.1449 mL | |
| 25 mM | 0.0686 mL | 0.3432 mL | 0.6864 mL | 1.7159 mL | |
| 30 mM | 0.0572 mL | 0.2860 mL | 0.5720 mL | 1.4300 mL | |
| 40 mM | 0.0429 mL | 0.2145 mL | 0.4290 mL | 1.0725 mL | |
| 50 mM | 0.0343 mL | 0.1716 mL | 0.3432 mL | 0.8580 mL | |
| 60 mM | 0.0286 mL | 0.1430 mL | 0.2860 mL | 0.7150 mL | |
| 80 mM | 0.0214 mL | 0.1072 mL | 0.2145 mL | 0.5362 mL |
Cy5.5-COOH Related Classifications
HY-D1040 Related Classifications
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