Cyclopentenyl uracil
Based on 1 Customer Validation
Cyclopentenyl uracil, a non-cytotoxic inhibitor of uridine kinase, effectively blocks the salvage of circulating uridine by host and tumor tissues in the intact mouse.
For research use only. We do not sell to patients.
- Purity: 99.84%
- CAS No.: 90597-20-9
- Formula: C10H12N2O5
- Molecular Weight:240.22
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
>100 μM
Compound: 52
|
In vitro cytotoxicity in CEM cells.
In vitro cytotoxicity in CEM cells.
|
[PMID: 11689085] |
| Vero | IC50 |
>100 μM
Compound: 52
|
In vitro cytotoxicity in vero cells.
In vitro cytotoxicity in vero cells.
|
[PMID: 11689085] |
Chemical Information
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CAS No. 90597-20-9
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Appearance Solid
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Molecular Weight 240.22
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Formula C10H12N2O5
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Color White to off-white
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SMILES
O[C@H]1[C@@](N2C(NC(C=C2)=O)=O)([H])C=C([C@H]1O)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (416.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1629 mL | 20.8147 mL | 41.6294 mL | 104.0734 mL |
| 5 mM | 0.8326 mL | 4.1629 mL | 8.3259 mL | 20.8147 mL | |
| 10 mM | 0.4163 mL | 2.0815 mL | 4.1629 mL | 10.4073 mL | |
| 15 mM | 0.2775 mL | 1.3876 mL | 2.7753 mL | 6.9382 mL | |
| 20 mM | 0.2081 mL | 1.0407 mL | 2.0815 mL | 5.2037 mL | |
| 25 mM | 0.1665 mL | 0.8326 mL | 1.6652 mL | 4.1629 mL | |
| 30 mM | 0.1388 mL | 0.6938 mL | 1.3876 mL | 3.4691 mL | |
| 40 mM | 0.1041 mL | 0.5204 mL | 1.0407 mL | 2.6018 mL | |
| 50 mM | 0.0833 mL | 0.4163 mL | 0.8326 mL | 2.0815 mL | |
| 60 mM | 0.0694 mL | 0.3469 mL | 0.6938 mL | 1.7346 mL | |
| 80 mM | 0.0520 mL | 0.2602 mL | 0.5204 mL | 1.3009 mL | |
| 100 mM | 0.0416 mL | 0.2081 mL | 0.4163 mL | 1.0407 mL |