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Cat. No.: HY-N14132

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Cyclothialidine E

Cyclothialidine E inhibits escherichia coli DNA helicases with an IC₅₀ of 0.7 μM.

For research use only. We do not sell to patients.

CAS No.: 194276-79-4
Formula: C₂₅H₃₃N₅O₁₁S
Molecular Weight:611.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Cyclothialidine E Chemical Structure

CAS No.: 194276-79-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cyclothialidine E inhibits escherichia coli DNA helicases with an IC₅₀ of 0.7 μM^[1].

IC₅₀ & Target

Helicase

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 194276-79-4
Molecular Weight 611.62
Formula C₂₅H₃₃N₅O₁₁S
SMILES

OC(CC[C@H](N)C(N1[C@@H]([C@@H](CC1)O)C(N[C@@H]2C(N[C@@H](CSCC3=C(O)C=C(O)C(C)=C3C(OC2)=O)C(N)=O)=O)=O)=O)=O
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Microorganisms
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. N Nakada, et al. Biological characterization of cyclothialidine, a new DNA gyrase inhibitor. Antimicrob Agents Chemother. 1993 Dec;37(12):2656-61. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Cyclothialidine E

All DNA/RNA Synthesis Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Cyclothialidine E Related Classifications

HY-N14132 Related Classifications