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  3. CysOx2

CysOx2 is a reaction-based fluorogenic probe for sulfenic acid (Ex/Em: 394/535 nm). CysOx2 can be used for detecting protein cysteine oxidation in living cells.

For research use only. We do not sell to patients.

CysOx2 Chemical Structure

CysOx2 Chemical Structure

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Description

CysOx2 is a reaction-based fluorogenic probe for sulfenic acid (Ex/Em: 394/535 nm). CysOx2 can be used for detecting protein cysteine oxidation in living cells[1].

IC50 & Target

Sulfenic acid[1]

In Vitro

CysOx2 (1 mM; 1 h) reacts with H2O2 and produces fluorescence in 50 mM HEPES pH 7.4[1].
CysOx2 is cell permeable[1].
CysOx2 (50 μM; 1 h) shows fluorescence signal in epitope-tagged wild-type EGFR expression HeLa cells, the signal is absent in C797S EGFR expression HeLa cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

305.32

Formula

C15H12FNO3S

SMILES

O=C1CS(=O)(C2=CC(F)=C(C3=CC=CC1=C32)N4CCC4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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CysOx2 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
CysOx2
Cat. No.:
HY-151505
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